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These Regions are big maps full of dynamic quests. You will spend many time there to complete all, while traveling around the map. As reward you will receive many resources and all kind of color sparks for your Atlas progress.
These Regions are not just instanced, you can log out and log in without losing your progress. Is some kind of hybrid between instanced and persistent. There are no channels, and no KS (Kill Steal), everyone can help each other to kill monsters, even without a party.