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I have a fairly decent rig. I would list the specs, but as I'll explain here it's not really relevant. My gf has a lesser computer (gts 8800 and 1gb ram). She can play just fine btw. Problem is on both of our computers the load times between campaign missions often is longer than two minutes. No exagerration. Google starcraft 2 load times. Lots of people have this issue and all their hardware is good. No one has a resolution other than get windows 7 ultimate, 4gb of ram, and a SSD. LOLLERSKATES my friends. None of those hardware upgrades are justified by anything graphics/sound-wise in SC2, and I find it to be a great game honestly.
However, it's frustrating because if you read enough search results on this, you see it's a real problem, happening to a lot of people, but apparently completely overlooked by most people who perhaps don't even play the campaign or perhaps their oversized rigs chew it up and spit it out. I don't know, but so far I've come across no possible fixes for this. I have no AV or anything else running, everything is defragged, other games run great.
One topic was interesting as someone surmised it had to do with internet verification, so I may try playing offline, but that seems unlikely. If anyone has any idea why this is happening, let me know. Please don't suggest I get a solid state drive though... because once something like that comes out of your virtual mouth, there's no putting it back in.