Will be a little while before they run out of reason to push Anthem onward. Got all that content to re-add back in. Once they run out of that, then they might consider dropping or doing a sequel.
Anthem 2 won't happen, the first is a dead duck and with Bioware being on the ropes, the only question now is DA4 if that game ends up being the last nail for Bioware or not.
I don't think they will shift focus to a sequel until they can prove it would be worth the effort. It's a weird trend with these lobby based loot grinding games to release very underwhelming. Destiny, The Division, Anthem now, they all released barebones and not great. But Destiny and The Division both managed to pull out of the ditch they were stuck in, maybe Anthem can follow the trend. I'm hoping they can because the game itself could be very great.
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https://www.fanatical.com/en/blog/anthem-2.0-bioware-sets-out-plans-to-overhaul-the-action-rpg