Skyrim Anime Overhaul (on MODDB)

TheScavenger

WARNING ITS NOT LORE FRIENDLY!

You can see screenshots and a video from the link

http://www.moddb.com/mods/skyrim-anime-overhaul

For the mod itself. It turns every NPC into a female, adds TONS of custom weapons/armor/items), adds thousands of new enemies, tons of new danger to Skyrim and makes the game actually quite a bit harder and more challenging. It also includes custom quests that you can't get anywhere else, and a bunch of other stuff. It also includes custom voices, and custom combat

TheScavenger

As a warning, it takes a high end PC to get good performance. As you can see in the screenshots and videos, it greatly expands the graphics quality of Skyrim