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1 : It completely alienates the PC fan base from EVE, short of those who are willing to shell out for 299 Dollar in the US and 1.500 NOK-159 British pounds or euro in Europe for a PS3.
2: The whole first impression of the game, including a race called Jovians which WAS orginally on DUST 514 official page, is now gone making the game much more unattractive to older Eve players who still are PC DIE HARDS.
3: To make the game not take advantage of Same Server as orginal game is a big FAIL, as this will make Ventrillo nigh to impossible from EVE to DUST514 unless CCP somehow make Unique channels for each of the guilds. Which will really defy the whole point of Dust 514 integration into the mainstream EVE.
4: To make a game thats a platform exclusive is one thing, but to make it completely opposite the main fanbase of EVE, is just plain suicide for a offspring mmo.
Just my 10 cents.
This will be yet another Tabula Rasa... Much overhyped. Too quick too short too far from the fanbase and deemed to fail from day one.