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From my research of the game, I feel the holy trinity may still exist in the game, using methods from GW1.
In GW1 there was no inherent threat mechanic, so the person who ran into the agro range first gets all the agro, holds onto it for 5-10 seconds, gets in position and using a specific set of very well combined skills, the group of mobs would die in a less than a second, is this still possible in GW2?
I understand threat mechanics are dead and burst healing is dead. But DPS is still very much alive with dummies, sustained healing still exists and there is still an armor stat.
What is stopping you from throwing the most tanky character possible, making him go into room first, pings when he is ready, everyone else stacks conditions while guardian gives sustained healing, there is your Holy Trinity again.
I really hope this doesn't happen, but since people are so used to it, they will find a way to force it.