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I've tested out these mods for 30+ hours, so maybe not the most extensive time. However there is no crashing, very stable and things work fine as far as I've seen. Maybe there could be conflicts, which I did go through before posting removed a few mods that were redundant. But I've played quite a bit and it all works (with no crashes or weird errors), which I think is definitely most important thing when it comes to mods.
Like title says though, definitely not for beginners and a lot of game changing mods (especially with cooking, aims to be more realistic/involved), plus Frackin universe is quite intimidating to begin with.
I've had a lot of fun thus far with this setup. So figured I'd share it and maybe someone else can have fun too.