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Chris Spears, Technical Director for Shroud of the Avatar, has posted a detailed description of SotA's new innovative combat UI.
In particular, note that the combat UI will feature a randomized placement of skills, rather than the traditional user defined placement of skills, on the combat hotbar.
EDIT: Sorry the youtube embed didn't work, just use the link. Sorry. I can't seem to delete the embed, either! /grumble