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Below is an excerpt from Divinity's Reach, a blog about Guild Wars 2.
Hope you enjoy!
"It's a question everyone asks themselves when they first play Guild Wars 2. You can have every little part of your character mapped out, log in, and that whole plan can be thrown immediately out the window. The whole process is actually very simple, but you need to account for the game being an MMO. Balance is in constant flux, one day you may have a God-like build and the next you may be sitting low on the totem pole. So how do you resist the urge to switch and cave in to your "grass is always greener" syndrome? Well to start, you need to find a profession that you can enjoy through the thick and thin, and the best way to do this is to like them. You can't just like a specific weapon, or "that flashy skill", you have to really, truly like them. Warts and all. Yes, even when their old and wrinkled as a prune. Now it may be sounding like I'm describing love, and you would be correct. If you want to choose that single character, the main profession for several years, you are going to have to love them."
The full article can be found here: http://divinitysreach.blogspot.com/2012/08/how-to-choose-profession.html#more
My Guild Wars 2 Blog can be found here: Divinity's Reach