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What kind of major changes do you think we will see?
I think gaming will become even more popular and thus more players for MMORPG's as the years go by and people get wealthier and wealthier and end up having more leisure time with nothing to do.
I think there will be new concepts for how an MMORPG is designed and how it's gameplay is handled, something quite drastically different than the basis of Everquest and games like World of Warcrafts gameplay. Also the action-element based MMORPG's of recent will take some unusual changes too I think.
Me personally, I'll keep a little bit of an eye out on how things are going, but I won't try out any games unless something just miraculousy captures me like how I felt about games when I was a young boy. Which are slim chances heh.